neutrophils, high lymphocytes low

It is most significant when the total neutrophil count is less than 0.5 x 10 9 /L, particularly when the neutropenia is due to impaired production (e.g. In these study, benign thyroid tumor were found in 16 years old subject as the youngest while 84 years old as the oldest, and for malignant thyroid nodule, the youngest subject is 16 years old and the oldest is 73 years old. In malignancies, 31 patients (59.6%) were more than 45 year old. This study were found 78 thyroid nodules in women (89.7%), with 46 subjects (58.9%) of them are malignant, and only 9 thyroid nodules in men (10.3%). Univariate analysis is used to describe each variable with frequency distribution table and to know the difference between variable by using chi square and t-test. All authors have contributed significantly, read and approved the final manuscript. myelodysplasia) can cause low neutrophil counts. When the number of neutrophils in the blood is low, it is called neutropenia. • LSCCs have low neutrophil/lymphocyte ratio (NLR) in the invasive front. Neutrophil, Lymphocyte, Thyroid nodule, Inflammation. Estrogens proote the growth of benign and malignant thyroid nodules by binding to these estrogen receptor nuclei and by activating the mitogen activated protein (MAP) kinase pathway thus mediating the occurrence of mitogenesis [10]. Neutrophilic leukocytosis occurs when a person has over 7,000 per mm3 mature neutrophils in their bloodstream. Oh, I forgot something, I was going through a divorce and my son had come to sleep in my bed within a week or 2 before his "I am tired" remark. In addition, NLR may also confirm benign FNA results in the thyroid, considering there are false negative values of 2% to 10%. Don't delay your care at Mayo Clinic. Hi, I think it would be very unlikely a leukemia, because a leukemia in neutrophils (neutrophilic myelogenous leukemia) would be very rare. These cancers develop three main pathological types of carcinomas: papillary thyroid carcinoma (PTC), follicular thyroid carcinoma (FTC) and anaplastic thyroid carcinoma (ATC). Patients were categorized into low grade (NLR ≤ 1,91) and high grade (NLR ≥ 1,92). • The low NLR and TB expression are in accordance with well-differentiated LSSCs. Neutrophils can also release substances to attract monocytes which, upon entering the tissue, differentiate to macrophages. They also help protect you against bacteria. These are one of the first immune cells to arrive at an inflamed or injured area and high neutrophils may be due to medical conditions like infection or stress. The study sample was chosen consecutively (consecutive sampling) i.e. Didn't find the answer you were looking for? There was statistically significant difference of neutrophillymphocyte ratio between benign thyroid nodule and malignant thyroid nodule. Neutrophil to lymphocyte ratio has emerged as a simple and valid composite marker of systemic inflammatory response. The following are the conditions for high lymphocytes: Tuberculosis. 32 years experience Psychiatry. Neutrophils are a type of white blood cell (WBC or granulocyte) that protect us from infections, among other functions. Patients with SLE were stratified based on the level of NLR as high (Hi) versus low (Lo), neutrophils (PMN) as Hi versus normal (norm), and lymphocytes (lymph) as Lo versus Norm. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. B-cell lymphocytopenia can lead to an increase in harmful and different types of infections. https://ic.steadyhealth.com/low-neutrophils-and-high-lymphocytes Chemotherapy, aplastic anaemia, Vitamin B12 deficiency and cancer (e.g. He has fatique, headaches and paleness a lot. This value is different from the value constraint proposed by Kocer et al. We evaluated neutrophil lymphocyte ratio with result post-operative patological anatomy. compared the NLR between those with an incidental papillary microcarcinoma and those with a benign goiter only and found that the former group had a significantly higher mean NLR than the latter group (3.0 vs. 1.9, p<0.001). My last one is actually on Monday. Dr. Alan Ali answered. Fine needle aspiration (FNA) cytology is generally considered the first line diagnostic test to screen for thyroid cancer. I had a biopsy of both lumps and they came back as benign. Stress Lymphocytes are much more specific to the organism causing the infection, and so for long-term infections, lymphocytes tend to be high and neutrophils lower since their job is essentially done. Thyroid nodules and malignant thyroid nodules are more common in women [9]. Estrogens is thought to be associated with increased incidence of thyroid nodules and thyroid cancer. Far more likely would be an infection, from bacteria, or fungus or even a parasite. WBC have been normal until now it is a little low, 4,64. Neutrophils and Lymphocytes: Neutrophils and lymphocytes are two specific types of white blood cells (other types of white blood cells include basophils. This study suggested that use of cutoff value of 1.91 for NLR would be optimum for clinical use to identify patients with PTC as sensitivity of 89% and specificity of 54.5% can be achieved. RPN designed, analyzed and interpreted the patient data. all subjects meeting the inclusion criteria and willing to participate in the study will be included without randomization. There were no symptoms that tipped me off before that day he came home from kindergarten, just what he said, and the fact he LOOKED tired, during the day...was SO out of character for him, he never took naps, was always running, NEVER sat still....until that day. Acute leukemia. We are gratefully indebted to our study participants in Dr. Sardjito General Hospital. Hi I talked to u yesterday about blood work. I had a mammogram and ultrasound done which showed a "thickening", but nothing to worry about (thier words...not mine). The oncology nurses were wonderful, and they keep you so informed at a teaching hospital, (I had the same access to the Leukemia information and books, pamphlets they were using, and would have the combination to the physicians library at the hospital) I HOPE your son doesn't have anything at all, and I hope if he does present with something, you have support, and wonderful nursses, (I was a single parent, and the nurses became MORE than just friends) The hospital you choose makes a big difference. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. SRI performed revising it critically for important intellectual content. Patients were categorized into low grade (NLR ≤ 1,91) and high grade (NLR ≥ 1,92). This is consistent with the results of this study which found 35 subjects (40.2%) with benign anatomic pathology and 52 subjects (59.8%) malignant, where the most malignancies were found in papillary carcinoma with 47 subjects (90.39%) and 15 of them are follicular variant. RBC: High neutrophils might indicate infection or effect of medication, low lymphocyte might indicate effect of medication or abnormality in lymphocytes, l ... Read More. The aim of this study is to examine the differences of neutrophil-lymphocyte ratio between benign thyroid nodule and malignant thyroid nodule. I can't imagine it taking another couple of years to find out why his Neutrophils are low. In most cases a neutrophil level must be over 8000 to be considered abnormally high and there are many causes of this high number. This is not much different from the existing literature. I know just them saying his name would make he feel better. It was also realized that my previous biopsy was really malignant, not benign as they first thought. Inflammation has been implicated in initiation and progression of thyroid cancer. All authors have contributed significantly, read and approved the final manuscript. The different groups were compared in their levels of (A) ICs, (B) type I IFN activity, (C) LDGs and (D) calprotectin (S100A8/A9). 1. A temporary increase in certain white blood cells, called lymphocytes, is normal after an infection. LSCCs have low CD66b + neutrophils and high CD3 + lymphocytes in the invasive front. In this study found 11 of 14 cases (78.6%) with FNA class V is a carcinoma. Even when the lymphocyte count remains the same, increasing the neutrophil count must lower the percentage of the lymphocytes. The authors are agree and responsible for the content and writing of the paper. His ... After having abnormal platelet counts my doctor ordered the BCR-ABL1 test which showed positive for CML or Ph+ALL. Recently, several inflammatory markers including pretreatment neutrophil to lymphocyte ratio (NLR), have being used as prognostic factors, since host inflammatory response to cancer is believed … My son presented with Acute Lymphoblastic Leukemia WITHOUT any previous symptoms. I looked at him, and not only was it not like him to be tired...evr practically, but he looked deathly sick, and it was suddenly! Background: Class III and IV of Bethesda classification is less conclusive in the diagnosis of thyroid cancer. Very bad stomach pains and ended up so tired. Research Article - Otolaryngology Online Journal (2018) Volume 8, Issue 2, 1Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine Community and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia, 2Faculty of Medicine, Tanjungpura University, Pontianak, Indonesia, Received date: May 09, 2018; Accepted date: June 19, 2018; Published date: June 25, 2018. Finally found a Dr. that said, true mono only once, after that, chronic Epstein-Barr virus. Neutrophil-lymphocyte ratio (NLR) of thyroid nodules is expected to assist in predicting the risk of malignancy in thyroid nodules, particularly in the results of FNA Bethesda systems class III and IV, which may help the selection of ases for surgery or conservative. It becomes second nature when your child is the issue. See also Symptoms of Acute myeloid leukemia; Mononucleosis; Ulcerative colitis. My 13 year old son's absolute neutrophil count has been low for at least 10 months starting at 1.72 in November and now to 8.8. Similarly, in Bethesda class VI found 4 out of 4 cases (100%) was a carcinoma in which a positive predictive value of malignant FNA interpretation was between 97-99% [7]. Those make the neutrophils go high to fight infection, and can make lymphocytes go low at the same time. Does it signify any disease. Too high a count can mean something more serious. Malignancy was found in 31 subjects (59.6%) ≥ 45 years old compared to benign nodule as much as 13 subjects (37.1%). Monocytes are related to the granulocyte family. Looking back, I think it was missed because they were looking for breast cancer, not NHL. The authors are agree and responsible for the content and writing of the paper. Lymphocytes. The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request. This month his Monocytes were high, 14, for the first time. We also express our gratitude to Department of Otorhinolaryngology-Head and Neck Surgery Faculty of Medicine Community and Nursing Universitas Gadjah Mada and to the Health Research Ethics Committee that gave permission, license and approved this research. The mediators and cellular effectors of inflammation are important constituents of the local environment of tumours [4]. Basophils. Always remember age-specific reference ranges for total WBC, neutrophil, and lymphocyte counts. I was stage 3, grade 3, which is more advanced, but the good thing about the kind of NHL I have is that catching it early doesn't really matter as they often wait until your more advanced anyways before they treat it. 30 yrs old Female asked about Low neutrophils and high lymphocytes, 1 doctor answered this and 13794 people found it useful. Has your son been checked for mono &/or chronic Epstein-Barr virus? I hope you keep posting, there was nothing like these forums when I went through it. monocytes, and eosinophils). By using this Site you agree to the following, By using this Site you agree to the following, Please help, need to understand my 5 year old sons results. This can lead to severe infections. The neutrophil-to-lymphocyte ratio (NLR), calculated by dividing the neutrophil count by the lymphocyte count, is used to determine the prognosis of an inflammatory reaction and is a component of routine blood count analys… The thyroid tissue express estrogen receptor, estrogen receptor α and β, where there is a significant increase of expression level in response to 17β-estradiol. The total WBC and neutrophil count in neonates younger than 1 … My 13 year old son's absolute neutrophil count has been low for at least 10 months starting at 1.72 in November and now to 8.8. WBC have been normal until now it is a little low… Once neutrophils arrive at tumour sites, they can be instructed by tumour-derived factors to “tune up” their supporting function. E-Mail: [email protected], © Allied Academies 2021 | Creative Commons License Open Access Journals by Allied Academies is licensed under a Creative Commons Attritbution 4.0 International License, All submissions of the EM system will be redirected to, 8th International Conference on COPD and Lung Health, 4th International Congress on Primary Health care and Nursing Education. Low neutrophils and high lymphocytes are generally present in viral infection. I went through chemotherapy for 6 months and then two years of maintenance treatments. They make up approximately 40 percent to 60 percent of the white blood cells in our bodies, and are the first cells to arrive on the scene when we experience a bacterial infection. Why did it take so long? How are you doing now? Ugh! We offer this Site AS IS and without any warranties. The authors declare that they have no competing interests. Even though advantages in treatment of CRC have being made over the last decades, the outcome remains poor. HIs absolute lymphocyte count has been high ranging from 2.47 to 3.99 and now 2.64. further research is required in determining the sensitivity and specificity values. When he died at 10, FRIENDS didn't know what to say, so it was really hard, I didn't want them to say anything, but please, don't just avoid the person because it is so scary. after chemotherapy). Normal (High end) Platelets, High Neutrophils, Low Lymphocytes (What does it mean)?.My doctor asked me to go for blood test because he suspected LUPUS.In the report everything was normal except Neutrophils(High), Lymphocytes (Low), Platelets 2 pts from being too high. • First study to analyze tumor budding in LSCCs, demonstrating its low expression. The early cells in the bone marrow that turn into monocytes are called monoblasts. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. Bacterial infections, stress, cancers (e.g. I hope you keep posting, and I know what you are going through (well, I realize everyone is different, but you know what I mean). The laboratory values are values with a maximum time limit of 1 week before operation, presented in categorical data with a cut of point value off 1.91. I went to a different doctor who did a needle punch biopsy and that came back as "suspicious for lymphoma", which was later confirmed. Kocer et al. DAE performed drafting the manuscript and give final approval of the version to be published. About 230.000 new cases of thyroid cancer were estimated in 2012 among women and 70.000 among men, with an agestandardized (world population) rate of 6.1/100.000 women and 1.9/100.000 men [2]. The neutrophil/lymphocyte ratio (NLR) is a simple index of systemic inflammatory response. Fine needle aspiration is the preferred method with good sensitivity and cost effectiveness in evaluating thyroid nodules [12]. Results: Thyroid nodule were dominant in 78 women patients (89.7%) and 46 patients (58.9%) were malignant. Causes of High Neutrophils. At this cut-off point negative predictive value was 92% [6]. Sed Rate is also high. She said she sees lots of low Neutrophils in those who has just herx a lot. My son had been feeling pretty good until last night. The 2 most frequently used markers of active inflammatory status in patients with cancer are C-reactive protein (CRP) and NLR, because they are reliable and widely available in daily clinical practice and their sensitivity in predicting survival rates has been supported by a large number of studies in various types of cancer [13]. Too high a count can mean something more serious. Neutrophils and lymphocytes constitute the first line of defense within the body against foreign invaders. I like my LLMD and trust that she knows what she's doing, but should I be concerned ? Only 37 subjects conducted while 50 subjects were not done FNA, this is not in accordance with American Thyroid Association (ATA) guidance recommendations in terms of early diagnosis in screening of thyroid nodules. The following year, I developed another lump on the same breast. Neutrophils also secrete the matrix metalloproteinase and serine protease that can damage the extracellular matrix and release bioactive growth factors and proangiogenic molecules and may stimulate local immunosuppression by disrupting T cell responses including cell death and T cell recruitment, alllowing growth, development and progression tumours [5]. Thirty seven subjects conducted by FNA, Bethesda class V is the most common results with 14 subjects. In this study obtained from 87 subjects, only 37 subjects conducted by FNA while 50 subjects were not done FNA. Current high lymphocyte and eosinophil count? Patients with elevated NLR have a relative lymphocytopenia and neutrophil leukocytosis in favor of protumour inflammatory response, in different types of cancer. Molecular testing as an additional examination is not always available. One day, when he was 5 he came home from school and said, "Mom, I'm tired but I'm not sleepy". RNL ≤ 1.91 is considered low and RNL ≥ 1.91 is considered high [6]. For people with Obsessive-Compulsive Disorder (OCD), the COVID-19 pandemic can be particularly challenging. I was in complete shoc... On the CBC report the normal range indicated a max of 3.1 so its barely over but i am still concerned. In this study, there were 87 patients who met the inclusion and exclusion criteria, according to the calculation of the sample size, the characteristic data of the research subjects can be seen in Table 1 below. (I'm sure it will be a much shorter time for your son.). Here’s how your baby’s growing in your body each week. He’s 33 years old, ordinarily healthy man. My diagnosis took so long because it was presenting in my breast, something that isn't very common with NHL. They had NO experience with the critical nature that even 5 minutes can make, and I had to really tell QUITE a few local doctors off, or he would have died! This may be due to changes in normal thyroid tissue and decreased immune systems occur in line with age [11]. It's kind of a long story. Estrogen receptors are intracellular receptors that serve as transcription factors. Is this anything I should be concerned about? The neutrophil count may be high with infe… In malignancies, 31 patients (59.6%) were more than 45 year old. Let me start off by saying this pertains to my husband. Results: Thyroid nodule were dominant in 78 women patients (89.7%) and 46 patients (58.9%) were malignant. Yay...I'm glad they were able to rule out Addison's and Hodgkins disease. The incidence of colorectal cancer (CRC) is expected to increase by 80% in year 2035. (Whoo-hoo!). Get your query answered 24*7 only on | Practo Consult Tumours have several chemotaxis mechanisms in regulating neutrophil recruitment through chemokines. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. 1 doctor agrees. A total of 288 PC patients diagnosed between January 1, 2012, and December 31, 2013, were retrospectively selected from a population-based electronic inpatients database. He never got the enlarged glands or bruises before presenting either, although during the 5 years of treatment, I knew MOST of the children did. Was told I would just have to live with it and rest whenever I had flares. Compared with serum CRP, which is not routinely measured as part of the cancer work up, NLR is inexpensive, easily calculated and universally available [14]. Wbc 9.8 and high neutrophils, 8.9 and a high absolute neutrophil. Low neutrophils, high lymphocytes Chery222. Then, in 2010, I developed a third lump on the same breast. A low neutrophil count along with a high lymphocyte count can be Sorry to hear about your Non-Hodgkin's lymphoma and that it took 3 years to diagnose. Adil Can Gungen*and Yusuf Aydemir Department of Pulmonology, Educatıon and Research Hospital, Sakarya University, Sakarya, Turkey *Corresponding Author: 1. So I know all kids are so different, and I had a wonderful Family doctor and was referred to Ucsf, and it there we had ALL our treatment. Adil Can Gungen Sakarya University Training and Research Hospital Sakarya, Turkey Accepted date:August 03, 2017 Citation: Gungen AC, Aydemir Y. The reported sensitivity of FNA for thyroid cancer is between 84% and 93% and specificity between 75% and 99% [3]. Many cancer survival studies have suggested that NLR is a significant predictor of overall. I never thought, like the saying goes, "It would happen to me, or HIM), but it does happen, to anybody, and maybe that is what scares people, the thought of a beautiful happy little boy getting sick and dying comes a little too close to home. The doctor said it was probably a virus but we have been dealing with him not feeling well for almost a year. I had mono at age 18. Thyroid nodule is a discrete lesion in the thyroid gland that is radiologically distinct from the surrounding thyroid parenchyma. A normal (absolute) neutrophil count is between 2500 and 7500 neutrophils per microliter of blood. Once he gets extra sleep and rest he seems to do better. (I had to use a couple of local ones just a very few times....they didn't WANT me to, and I didn't WANT to use them! Papillary thyroid carcinoma consists of 85-90% of all thyroid cancer cases growth, followed by FTC (5-10%) [8]. The most common reason for an elevated neutrophil count is from infection, and usually a bacterial infection. All funding from this study come from authors its self. neutrophil and lymphocyte counts measured at disease diagnosis on the overall survival (OS) of PC. This study aims to examine the differences of neutrophil-lymphocyte ratio between benign thyroid nodule and malignant thyroid nodule. Call: 44 2033180199 People with CLL may have very high white blood cell counts because of excess numbers of lymphocytes (lymphocytosis), but the leukemia cells don't fight infection the way normal white blood cells do. All participants give their consent to participate in this study and that the information will be published in this journal. You might hear the term neutropenia, which refers to low levels of neutrophils (a type of granulocyte needed to fight bacterial infections). NLR was calculated by dividing preoperative neutrophil count with lymphocyte count. low "Neutrophils" high "Lymph" Low "Neutrophils (Absolute)" normal "Lymph (Absolute)" My LLMD said it's fine. His neutrophil count and his Blasts were the first signs, and even they couldn't believe he wasn't "sick",  (of course he had to be) until the day he was dying. Sample in this research is patient with thyroid nodule who comes to Dr. Sardjito hospital from January, 2016 to April, 2017 that meets the inclusion and exclusion criteria. In this study, mean NLR was found in benign thyroid tumours 1.85 and 2.56 in malignant thyroid tumours, which statistically significant difference (p=0,0001). Hopefully, whatever it is they find, will be minor and easy to treat. The only reason that the percentage of lymphocytes is "low" is because the neutrophil count is so high. Conclusion: There was statistically significant difference of neutrophil-lymphocyte ratio between benign thyroid nodule and malignant thyroid nodule. In this study, patients with NLR ≥ 1.92 and malignant nodules were 40 patients from 55 patients and NLR ≤ 1.91 and benign nodules were 20 patients from 32 patients, which was statistically significant difference (p=0,001) [9]. However, stress or steroid use can also cause an eosinophil count to be low. I developed a small lump in my breast back in 2007. A couple of yrs later, presented with mono-type symptoms again but was told you could only have mono once. The authors concluded that NLR could potentially be used as a biomarker for detecting incidental small PTC in an apparently benign goiter [15]. When asked about the Lymph, she said it's OK. Low levels of T cells or too few NK cells can lead to uncontrolled viral, fungal, and parasitic infections. Levels of less than 0.5 mcL are considered severe low levels of neutrophils Normal adult levels of neutrophils are about 1,500 to 8,000 or 1.5 to 8.0 neutrophils per microliters (mcL) High levels of neutrophils are more than 8000 neutrophils per mcL or 8.0 mcL What Does It Mean When Your Neutrophils Are High? 2017;1(1):1-4. Neutrophils and lymphocytes are the first inflammation and regulatory markers, respectively, found in injured areas. An interview with the co-discoverer of one of the biggest breakthroughs in cancer research, From causes to treatment options, get answers to your questions about CML, a type of blood cancer, New drug options on the horizon may make CML, a type of blood cancer, one of the few success stories in cancer treatment. I have 5 year old son who has been sick a lot, most recently having fevers 3 weeks apart with no one else in the house getting sick. The increased level of lymphocytes helps the body to fight the infection. A blood differential test will measure the levels of neutrophils and lymphocytes, and it is often used to confirm a high neutrophils-low lymphocytes problem like an infection, anemia, leukemia, and other diseases. Exclusion criteria in this research are: (1) Thyroid nodules with infectious diseases; (2) Core biopsy without anatomical pathology results. His Neutrophil count was ZERO, and that was always the scariest part, always, (It would linger so low, even when he was on chemo, and during periods he was at his "best". It took a total of 3 years to get my diagnosis on Non-Hodgkin's lymphoma, so don't give up! A list of national and international resources and hotlines to help connect you to needed health and medical services. It's good to hear that they aren't going to give up trying to find a diagnosis. NEUTROPENIA (LOW NEUTROPHIL COUNT) Neutropenia is potentially associated with life threatening infection. Moving further away from avg over two years LY: 49.4% NE: 27.4% EO: 13.1% Scared of leukemia or lymphoma, tested negative for hep B and C, have allergies and cat allergies The correlation between asthma disease and neutrophil to lymphocyte ratio.. Res J Allergy Immunol. Nevertheless the use of NLR should not be considered a decisive factor but it only provides an option in strengthening the diagnosis, since histopathology is a gold standard in diagnosis. Thyroid nodules can be caused by many disorders: benign (colloid nodule, Hashimoto’s thyroiditis, simple or hemorrhagic cyst, follicular adenoma and subacute thyroiditis) and malignant (papillary cancer, follicular cancer, hurthle cell (oncocytic) cancer, anaplastic cancer, mmedullary cancer, thyroid lymphoma and metastases) [1]. Methods: Eighty seven patients with benign and malignant thyroid nodule were analyzed retrospectively. Ethics approval and consent to participate, Medical and Health Research Ethics Committee (MHREC) Faculty of Medicine Gadjah Mada University-Dr.Sardjito Hospital, The Medical and Health Research Ethics Committe (MHREC) states that the protocol meets the ethical principle outlined in the Declaration of Helsinki 2008 and therefore can be carried out. The lower blood level limit for neutrophils in … Subscribe to MedHelp's free newsletter for Community Support, Experience, and Guidance. leukaemia) and trauma can cause high neutrophil counts. I'll make a long horrible story short by saying he was admitted to UCSF in San Francisco because I convinced my Family Doctor, (He had NEVER been sick before, he was the healthiest baby, child, up until that moment I had ever known...he was my youngest out of 3 children, and my only boy. Complete blood counts with differential counts were taken before operation. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. My lymphs were low, 1 … read more Schedule your appointment now for safe in-person care. I was praying for Ebstein-Barr, which took the longest to get the results back from, but EVERYTHING was negative, and then he presented with 99.9% Blasts and it was confirmed.

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